Book The Best Hotels in Wilson City, MO for 2026 from CA $81 - Fully Refundable Options

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Our top choices for Wilson City hotels

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a counter, a flat-screen TV, and a window with blinds.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

CA $84

CA $93 total

includes taxes & fees

Sep 28 - Sep 29

A building with a fountain and flower beds in front.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

2. The Riverstone Hotel Charleston-Sikeston

Charleston

Jay

CA $94

CA $104 total

includes taxes & fees

Sep 27 - Sep 28

A hotel lobby with a reception desk, seating area, and a large window.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

A hotel room with a desk, chair, television, and a lamp.

A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

3. Quality Inn Cairo I-57

Cairo

Santiago

CA $100

CA $111 total

includes taxes & fees

Oct 2 - Oct 3

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

4. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

CA $151

CA $174 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

5. Eagle Inn Charleston

Charleston

Jackson

CA $109

CA $120 total

includes taxes & fees

Sep 30 - Oct 1

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

6. Best Western Plus Sikeston I-55

Sikeston

Shelley

CA $123

CA $141 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Sharika West

CA $89

CA $102 total

includes taxes & fees

Oct 11 - Oct 12

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious lobby with a central atrium, a piano, and a reception desk.

8. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

CA $94

CA $107 total

includes taxes & fees

Sep 30 - Oct 1

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

A living room with two sofas, a coffee table, a TV, and a cabinet.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

9. Comfort Inn & Suites Sikeston I-55

Sikeston

Starlette

CA $126

CA $144 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.

A bathroom with yellow walls, a wooden cabinet, a sink, a mirror, and a hanging towel rack.

A motel with a red roof and beige walls, a parking lot, and a signboard.

A reception desk with a computer, a framed picture on the wall, and a vase with flowers.

10. La Center Motel

La Center

Carrie

CA $69

CA $81 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A motel with a covered entrance, multiple rooms, and a parking lot.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

11. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

William

CA $81

CA $92 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

12. Country Yard Inn and Suite

Sikeston

William

CA $79

CA $94 total

includes taxes & fees

Sep 27 - Sep 28

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Top Wilson City Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"The hall ways smelled so good but we did get dirty blankets . They have many restaurants and stores options really closed by so if you have children it is a great spot to stop specifically since is just in the entry or exit of the hwy ."

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"."

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent

"Súper affordable pricing, and the property was clean and comfortable! Complimentary breakfast was a plus!"

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a very good value. It has been the best hotel I've stayed at in awhile."

Cozy cabins on beautiful Horseshoe Lake

10/10 Excellent

"Super communication! . Accommodating. Nice people"

The Riverstone Hotel Charleston-Sikeston

8/10 Good

"Overall it was excellant, other then the toilet running constantly... Pool could have been cleaner, considering the heat-wave they were having............."

Quality Inn Cairo I-57

8/10 Good

"Good service,nice stuff and no complaints"

La Center Motel

10/10 Excellent

"Great AC unit in the room!"